mouse TECT1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Tctn1.
shAAV-274013
AAV-m-TECT1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Tctn1 (tectonic family member 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
G730031O11Rik; Tect1
Description (Vector)
Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Regulator of Hedgehog (Hh), required for both activation and inhibition of the Hh pathway in the patterning of the neural tube. During neural tube development, it is required for formation of the most ventral cell types and for full Hh pathway activation. Functions in Hh signal transduction to fully activate the pathway in the presence of high Hh levels and to repress the pathway in the absence of Hh signals. Modulates Hh signal transduction downstream of SMO and RAB23 (By similarity).
Gene ID
654470
Gene Name (Vector)
tectonic family member 1
Gene Symbol
Tctn1
ORF Size (aa)
1782
ORF Size (bp)
1782 bp
RefSeq ID
NM_001039153
RefSeq Synonyms
NM_001039153, BC156783,
Species
mouse
UniGene ID
Mm.375934
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.