mouse TBXA2R shRNA silencing AAV

Name
AAV-m-TBXA2R-shRNA

Cat No
shAAV-273879

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Mouse Tbxa2r.

shAAV-273879

AAV-m-TBXA2R-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Tbxa2r (thromboxane A2 receptor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

TP; TXA2-R

Description (Vector)

Receptor for thromboxane A2 (TXA2), a potent stimulator of platelet aggregation. The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system. In the kidney, the binding of TXA2 to glomerular TP receptors causes intense vasoconstriction. Activates phospholipase C. Isoform 1 activates adenylyl cyclase. Isoform 2 inhibits adenylyl cyclase.

Gene ID

21390

Gene Name (Vector)

thromboxane A2 receptor

Gene Symbol

Tbxa2r

ORF Size (aa)

1026

ORF Size (bp)

1026 bp

RefSeq ID

NM_009325

RefSeq Synonyms

NM_009325, NM_001277265, BC138886, BC138885, BC089611,

Species

mouse

UniGene ID

Mm.4545

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.