mouse TAOK3 shRNA silencing AAV

Name
AAV-m-TAOK3-shRNA

Cat No
shAAV-273690

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Mouse Taok3.

shAAV-273690

AAV-m-TAOK3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Taok3 (TAO kinase 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

2900006A08Rik; A130052D22; A430105I05Rik

Description (Vector)

Serine/threonine-protein kinase that acts as a regulator of the p38/MAPK14 stress-activated MAPK cascade and of the MAPK8/JNK cascade. Acts as an activator of the p38/MAPK14 stress-activated MAPK cascade. In response to DNA damage, involved in the G2/M transition DNA damage checkpoint by activating the p38/MAPK14 stress-activated MAPK cascade, probably by mediating phosphorylation of upstream MAP2K3 and MAP2K6 kinases. Inhibits basal activity of MAPK8/JNK cascade and diminishes its activation in response epidermal growth factor (EGF).

Gene ID

330177

Gene Name (Vector)

TAO kinase 3

Gene Symbol

Taok3

ORF Size (aa)

2697

ORF Size (bp)

2697 bp

RefSeq ID

NM_001081308

RefSeq Synonyms

NM_183306, NM_001199685, NM_001081308, BC158072,

Species

mouse

UniGene ID

Mm.248296

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.