mouse SUZ12 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Suz12.
shAAV-273490
AAV-m-SUZ12-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Suz12 (suppressor of zeste 12 homolog (Drosophila)). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
2610028O16Rik; AI195385; AU016842; AW536442; D11Ertd530e; mKIAA0160
Description (Vector)
Polycomb group (PcG) protein. Component of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' (H3K9me) and 'Lys-27' (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene. The PRC2/EED-EZH2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems. Genes repressed by the PRC2/EED-EZH2 complex include HOXC8, HOXA9, MYT1 and CDKN2A.
Gene ID
52615
Gene Name (Vector)
suppressor of zeste 12 homolog (Drosophila)
Gene Symbol
Suz12
ORF Size (aa)
2226
ORF Size (bp)
2226 bp
RefSeq ID
NM_199196
RefSeq Synonyms
NM_199196, NM_001163018, BC064461,
Species
mouse
UniGene ID
Mm.473315
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.