mouse STXBP1 shRNA silencing AAV

Name
AAV-m-STXBP1-shRNA

Cat No
shAAV-273417

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Mouse Stxbp1.

shAAV-273417

AAV-m-STXBP1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Stxbp1 (syntaxin binding protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

AI317162; AI326233; MMS10-G; Ms10g; Munc-18a; Munc18-1; N-sec1; nsec1; Rb-sec1; Sxtbp1; Unc18-1; Unc18h

Description (Vector)

STXBP1 may participate in the regulation of synaptic vesicle docking and fusion, possibly through interaction with GTP-binding proteins. Essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio. Can interact with syntaxins 1, 2, and 3 but not syntaxin 4. May play a role in determining the specificity of intracellular fusion reactions.

Gene ID

20910

Gene Name (Vector)

syntaxin binding protein 1

Gene Symbol

Stxbp1

ORF Size (aa)

1812

ORF Size (bp)

1812 bp

RefSeq ID

NM_009295

RefSeq Synonyms

NM_009295, NM_001113569, BC031728,

Species

mouse

UniGene ID

Mm.278865

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.