mouse SRRM1 shRNA silencing AAV

Name
AAV-m-SRRM1-shRNA

Cat No
shAAV-273164

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Mouse Srrm1.

shAAV-273164

AAV-m-SRRM1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Srrm1 (serine/arginine repetitive matrix 1). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

AA407769; POP101; Srm160

Description (Vector)

Part of pre- and post-splicing multiprotein mRNP complexes. Involved in numerous pre-mRNA processing events. Promotes constitutive and exonic splicing enhancer (ESE)-dependent splicing activation by bridging together sequence-specific (SR family proteins, SFRS4, SFRS5 and TRA2B/SFRS10) and basal snRNP (SNRP70 and SNRPA1) factors of the spliceosome. Stimulates mRNA 3'-end cleavage independently of the formation of an exon junction complex. Binds both pre-mRNA and spliced mRNA 20-25 nt upstream of exon-exon junctions. Binds RNA and DNA with low sequence specificity and has similar preference for either double- or single-stranded nucleic acid substrates.

Gene ID

51796

Gene Name (Vector)

serine/arginine repetitive matrix 1

Gene Symbol

Srrm1

ORF Size (aa)

2841

ORF Size (bp)

2841 bp

RefSeq ID

NM_016799

RefSeq Synonyms

NM_016799, NM_001130477, BC094322,

Species

mouse

UniGene ID

Mm.1963

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.