mouse SRGAP1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Srgap1.
shAAV-273131
AAV-m-SRGAP1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Srgap1 (SLIT-ROBO Rho GTPase activating protein 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
4930572H05Rik; Arhgap13
Description (Vector)
GTPase-activating protein for RhoA and Cdc42 small GTPases. Together with CDC42 seems to be involved in the pathway mediating the repulsive signaling of Robo and Slit proteins in neuronal migration. SLIT2, probably through interaction with ROBO1, increases the interaction of SRGAP1 with ROBO1 and inactivates CDC42.
Gene ID
117600
Gene Name (Vector)
SLIT-ROBO Rho GTPase activating protein 1
Gene Symbol
Srgap1
ORF Size (aa)
3189
ORF Size (bp)
3189 bp
RefSeq ID
NM_001081037
RefSeq Synonyms
NM_001242411, NM_001081037, BC120893, BC120892,
Species
mouse
UniGene ID
Mm.288698
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.