mouse SRD5A3 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Srd5a3.
shAAV-273125
AAV-m-SRD5A3-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Srd5a3 (steroid 5 alpha-reductase 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
1110025P14Rik; A430076C09; AV364670; AW987574; D730040M03Rik; H5ar; S5AR 3; Srd5a2l
Description (Vector)
Probable polyprenol reductase. Plays a key role in early steps of protein N-linked glycosylation by being required for the conversion of polyprenol into dolichol. Dolichols are required for the synthesis of dolichol-linked monosaccharides and the oligosaccharide precursor used for N-glycosylation. Probably acts as a polyprenol reductase that promotes the reduction of the alpha-isoprene unit of polyprenols into dolichols in a NADP-dependent mechanism. Also able to convert testosterone (T) into 5-alpha-dihydrotestosterone (DHT).
Gene ID
57357
Gene Name (Vector)
steroid 5 alpha-reductase 3
Gene Symbol
Srd5a3
ORF Size (aa)
993
ORF Size (bp)
993 bp
RefSeq ID
NM_020611
RefSeq Synonyms
NM_020611, BC145647, BC014771,
Species
mouse
UniGene ID
Mm.289446
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.