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mouse SPO11 shRNA silencing AAV

Name 
AAV-m-SPO11-shRNA
Cat No 
shAAV-273045
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Spo11.

shAAV-273045
AAV-m-SPO11-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Spo11 (SPO11 meiotic protein covalently bound to DSB). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AI449549; Spo11a; Spo11b
Description (Vector)
Required for meiotic recombination. Mediates DNA cleavage that forms the double-strand breaks (DSB) that initiate meiotic recombination (By similarity).
Gene ID
26972
Gene Name (Vector)
SPO11 meiotic protein covalently bound to DSB
Gene Symbol
Spo11
ORF Size (aa)
1191
ORF Size (bp)
1191 bp
RefSeq ID
NM_012046
RefSeq Synonyms
NM_012046, NM_001305434, NM_001083960, NM_001083959, BC156813,
Species
mouse
UniGene ID
Mm.23495

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.