mouse SPATA13 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Spata13.
shAAV-272939
AAV-m-SPATA13-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Spata13 (spermatogenesis associated 13). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
C79050; ESTM11; mFLJ00298; X83327
Description (Vector)
Acts as guanine nucleotide exchange factor (GEF) for RHOA, RAC1 and CDC42 GTPases. Regulates cell migration and adhesion assembly and disassembly through a RAC1, PI3K, RHOA and AKT1-dependent mechanism. Increases both RAC1 and CDC42 activity, but decreases the amount of active RHOA. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Involved in tumor angiogenesis and may play a role in intestinal adenoma formation and tumor progression.
Gene ID
219140
Gene Name (Vector)
spermatogenesis associated 13
Gene Symbol
Spata13
ORF Size (aa)
3450
ORF Size (bp)
3450 bp
RefSeq ID
NM_001033272
RefSeq Synonyms
NM_001310594, NM_001033272, BC145285, BC138455,
Species
mouse
UniGene ID
Mm.149776
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.