human HIP1R Over-expression AAV

Name 
AAV-h-HIP1R
Cat No 
AAV-211039
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human HIP1R.

AAV-211039
AAV-h-HIP1R

Ready-to-use AAV expressing Human HIP1R (huntingtin interacting protein 1 related). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
HIP12; HIP-12; HIP1-related protein; HIP3; huntingtin interacting protein 12; Huntingtin-interacting protein 12; huntingtin-interacting protein 1-related protein; ILWEQ
Description (eCommerce)
HIP1R is a component of clathrin-coated pits and vesicles, that may link the endocytic machinery to the actin cytoskeleton. It binds 3-phosphoinositides (via ENTH domain). HIP1R may act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O75146].
Gene ID
9026
Gene Name (eCommerce)
huntingtin interacting protein 1 related
Gene Name (Vector)
huntingtin interacting protein 1 related
Gene Symbol
HIP1R
HGNC ID
HGNC:18415
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1848
ORF Size (bp)
1848 bp
Protein Name (eCommerce)
Huntingtin-interacting protein 1-related protein
RefSeq ID
NM_003959
RefSeq Synonyms
NM_003959, NM_001303099, NM_001303097, BC067085,
Research Areas
Cytoskeleton,Golgi Apparatus
Research Areas (Faceted)
cell_biology
Species
human
Target Sentence
HIP1R is a component of clathrin-coated pits and vesicles, that may link the endocytic machinery to the actin cytoskeleton. It binds 3-phosphoinositides (via ENTH domain). HIP1R may act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O75146].
UniGene ID
Hs.714965
UniProt ID (eCommerce)
O75146

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.