mouse SMYD2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Smyd2.
shAAV-272692
AAV-m-SMYD2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Smyd2 (SET and MYND domain containing 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
1110020E07Rik; 4930402C15; KMT3C; Zmynd14
Description (Vector)
Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins. Specifically methylates histone H3 'Lys-4' (H3K4me) and dimethylates histone H3 'Lys-36' (H3K36me2). Has also methyltransferase activity toward non-histone proteins such as p53/TP53 and RB1. Monomethylates 'Lys-370' of p53/TP53, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity of p53/TP53. Monomethylates 'Lys-860' of RB1/RB.
Gene ID
226830
Gene Name (Vector)
SET and MYND domain containing 2
Gene Symbol
Smyd2
ORF Size (aa)
1302
ORF Size (bp)
1302 bp
RefSeq ID
NM_026796
RefSeq Synonyms
NM_026796, BC023119,
Species
mouse
UniGene ID
Mm.156895
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.