mouse SLC27A5 shRNA silencing AAV

Name
AAV-m-SLC27A5-shRNA

Cat No
shAAV-272269

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Mouse Slc27a5.

shAAV-272269

AAV-m-SLC27A5-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Slc27a5 (solute carrier family 27 (fatty acid transporter), member 5). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

FACVL3; FATP5; Vlacsr; VLCS-H2; VLCSH2

Description (Vector)

Acyl-CoA synthetase involved in bile acid metabolism. Proposed to catalyze the first step in the conjugation of C24 bile acids (choloneates) to glycine and taurine before excretion into bile canaliculi by activating them to their CoA thioesters. Seems to activate secondary bile acids entering the liver from the enterohepatic circulation. In vitro, also activates 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate (THCA), the C27 precursor of cholic acid deriving from the de novo synthesis from cholesterol.

Gene ID

26459

Gene Name (Vector)

solute carrier family 27 (fatty acid transporter), member 5

Gene Symbol

Slc27a5

ORF Size (aa)

2070

ORF Size (bp)

2070 bp

RefSeq ID

NM_009512

RefSeq Synonyms

NM_009512, BC145825, BC145823, BC115421, BC013335, BC013272,

Species

mouse

UniGene ID

Mm.10984

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.