mouse SH3PXD2A shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Sh3pxd2a.
shAAV-271917
AAV-m-SH3PXD2A-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Sh3pxd2a (SH3 and PX domains 2A). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
2310014D11Rik; AA589508; AI256723; AI413738; C230050L11; EG329070; Fish; Gm5098; Sh3md1; Tks5; TSK5
Description (Vector)
Adapter protein involved in invadopodia and podosome formation, extracellular matrix degradation and invasiveness of some cancer cells. Binds matrix metalloproteinases (ADAMs), NADPH oxidases (NOXs) and phosphoinositides. Acts as an organizer protein that allows NOX1- or NOX3-dependent reactive oxygen species (ROS) generation and ROS localization. In association with ADAM12, mediates the neurotoxic effect of beta-amyloid peptide.
Gene ID
14218
Gene Name (Vector)
SH3 and PX domains 2A
Gene Symbol
Sh3pxd2a
ORF Size (aa)
2433
ORF Size (bp)
2433 bp
RefSeq ID
NM_008018
RefSeq Synonyms
NM_008018, NM_001164717, BC118022,
Species
mouse
UniGene ID
Mm.392005
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.