mouse SETMAR shRNA silencing AAV

Name 
AAV-m-SETMAR-shRNA
Cat No 
shAAV-271767
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Setmar.

shAAV-271767
AAV-m-SETMAR-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Setmar (SET domain without mariner transposase fusion). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
5830404F24Rik; Etet2
Description (Vector)
Histone methyltransferase that methylates 'Lys-4' and 'Lys-36' of histone H3, 2 specific tags for epigenetic transcriptional activation. Specifically mediates dimethylation of H3 'Lys-36'. Has sequence-specific DNA-binding activity and recognizes the 19-mer core of the 5'-terminal inverted repeats (TIRs) of the Hsmar1 element. Has DNA nicking activity. Has in vivo end joining activity and may mediate genomic integration of foreign DNA.
Gene ID
74729
Gene Name (Vector)
SET domain without mariner transposase fusion
Gene Symbol
Setmar
ORF Size (aa)
930
ORF Size (bp)
930 bp
RefSeq ID
NM_178391
RefSeq Synonyms
NM_178391, NM_001276356, BC045208,
Species
mouse
UniGene ID
Mm.56539

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.