mouse SEMA4A shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Sema4a.
shAAV-271589
AAV-m-SEMA4A-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Sema4a (sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AI132332; Semab; SemB
Description (Vector)
Cell surface receptor for PLXNB1, PLXNB2, PLXNB3 and PLXND1 that plays an important role in cell-cell signaling. Plays a role in priming antigen-specific T cells, promotes differentiation of Th1 T helper cells, and thereby contributes to adaptive immunity. Promotes phosphorylation of TIMD2. Inhibits angiogenesis. Promotes axon growth cone collapse. Inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons (By similarity).
Gene ID
20351
Gene Name (Vector)
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
Gene Symbol
Sema4a
ORF Size (aa)
2283
ORF Size (bp)
2283 bp
RefSeq ID
NM_013658
RefSeq Synonyms
NM_013658, NM_001163491, NM_001163490, NM_001163489, BC025800,
Species
mouse
UniGene ID
Mm.439752
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.