mouse SCN2B shRNA silencing AAV

Name 
AAV-m-SCN2B-shRNA
Cat No 
shAAV-271445
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Scn2b.

shAAV-271445
AAV-m-SCN2B-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Scn2b (sodium channel, voltage-gated, type II, beta). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
2810451E09Rik; AI840361; Gm183
Description (Vector)
Crucial in the assembly, expression, and functional modulation of the heterotrimeric complex of the sodium channel. The subunit beta-2 causes an increase in the plasma membrane surface area and in its folding into microvilli. Interacts with TNR may play a crucial role in clustering and regulation of activity of sodium channels at nodes of Ranvier (By similarity).
Gene ID
72821
Gene Name (Vector)
sodium channel, voltage-gated, type II, beta
Gene Symbol
Scn2b
ORF Size (aa)
648
ORF Size (bp)
648 bp
RefSeq ID
NM_001014761
RefSeq Synonyms
NM_001014761, BC092225,
Species
mouse
UniGene ID
Mm.477575

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.