mouse SCN10A shRNA silencing AAV

Name
AAV-m-SCN10A-shRNA

Cat No
shAAV-271442

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Mouse Scn10a.

shAAV-271442

AAV-m-SCN10A-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Scn10a (sodium channel, voltage-gated, type X, alpha). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

Nav1.8; PN3; SNS

Description (Vector)

This protein mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which sodium ions may pass in accordance with their electrochemical gradient. It is a tetrodotoxin-resistant sodium channel isoform. Its electrophysiological properties vary depending on the type of the associated beta subunits (in vitro). Plays a role in neuropathic pain mechanisms (By similarity).

Gene ID

20264

Gene Name (Vector)

sodium channel, voltage-gated, type X, alpha

Gene Symbol

Scn10a

ORF Size (aa)

5871

ORF Size (bp)

5871 bp

RefSeq ID

NM_009134

RefSeq Synonyms

NM_009134, NM_001205321, BC156475,

Species

mouse

UniGene ID

Mm.247042

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.