mouse S1PR5 shRNA silencing AAV

Name 
AAV-m-S1PR5-shRNA
Cat No 
shAAV-271313
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse S1pr5.

shAAV-271313
AAV-m-S1PR5-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse S1pr5 (sphingosine-1-phosphate receptor 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Edg8; lpB4; S1P5
Description (Vector)
Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. Is coupled to both the G(i/0)alpha and G(12) subclass of heteromeric G-proteins (By similarity). May play a regulatory role in the transformation of radial glial cells into astrocytes and may affect proliferative activity of these cells.
Gene ID
94226
Gene Name (Vector)
sphingosine-1-phosphate receptor 5
Gene Symbol
S1pr5
ORF Size (aa)
1203
ORF Size (bp)
1203 bp
RefSeq ID
NM_053190
RefSeq Synonyms
NM_053190, BC012232,
Species
mouse
UniGene ID
Mm.190619

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.