human HDC Over-expression AAV

Name
AAV-h-HDC

Cat No
AAV-210898

Availability
4-5 weeks

This is an AAV expressing Human HDC.

AAV-210898

AAV-h-HDC

Ready-to-use AAV expressing Human HDC (histidine decarboxylase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Description (Vector)

HDC encodes a member of the group II decarboxylase family and forms a homodimer that converts L-histidine to histamine in a pyridoxal phosphate dependent manner. Histamine regulates several physiologic processes, including neurotransmission, gastric acid secretion,inflamation, and smooth muscle tone.

Gene ID

3067

Gene Name (Vector)

histidine decarboxylase

Gene Symbol

HDC

HGNC ID

HGNC:4855

ORF Size (aa)

1890

ORF Size (bp)

1890 bp

RefSeq ID

NM_002112

RefSeq Synonyms

NM_002112, NM_001306146, BC144173, BC130527,

Species

human

UniGene ID

Hs.1481

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.