mouse S100B shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse S100b.
shAAV-271302
AAV-m-S100B-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse S100b (S100 protein, beta polypeptide, neural). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AI850290; Bpb
Description (Vector)
Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling (By similarity).
Gene ID
20203
Gene Name (Vector)
S100 protein, beta polypeptide, neural
Gene Symbol
S100b
ORF Size (aa)
279
RefSeq ID
NM_009115
RefSeq Synonyms
NM_009115, BC061178,
Species
mouse
UniGene ID
Mm.235998
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.