mouse RYK shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Ryk.
shAAV-271281
AAV-m-RYK-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Ryk (receptor-like tyrosine kinase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AW536699; ERK-3; Vik
Description (Vector)
RYK may be a coreceptor along with FZD8 of Wnt proteins, such as WNT1, WNT3, WNT3A and WNT5A. Involved in neuron differentiation, axon guidance, corpus callosum establishment and neurite outgrowth. In response to WNT3 stimulation, receptor C-terminal cleavage occurs in its transmembrane region and allows the C-terminal intracellular product to translocate from the cytoplasm to the nucleus where it plays a crucial role in neuronal development.
Gene ID
20187
Gene Name (Vector)
receptor-like tyrosine kinase
Gene Symbol
Ryk
ORF Size (aa)
1428
ORF Size (bp)
1428 bp
RefSeq ID
NM_013649
RefSeq Synonyms
NM_013649, NM_001284258, NM_001042607, BC032275,
Species
mouse
UniGene ID
Mm.335391
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.