mouse RTN3 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Rtn3.
shAAV-271221
AAV-m-RTN3-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Rtn3 (reticulon 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
RTN3-A1
Description (Vector)
RTN3 may be involved in membrane trafficking in the early secretory pathway. Inhibits BACE1 activity and amyloid precursor protein processing. May induce caspase-8 cascade and apoptosis. May favor BCL2 translocation to the mitochondria upon endoplasmic reticulum stress. In case of enteroviruses infection, RTN3 may be involved in the viral replication or pathogenesis.
Gene ID
20168
Gene Name (Vector)
reticulon 3
Gene Symbol
Rtn3
ORF Size (aa)
2895
ORF Size (bp)
2895 bp
RefSeq ID
NM_053076
RefSeq Synonyms
NM_053076, NM_001271487, NM_001271486, NM_001003934, NM_001003933, BC079882,
Species
mouse
UniGene ID
Mm.453608
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.