mouse RRM2B shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Rrm2b.
shAAV-271149
AAV-m-RRM2B-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Rrm2b (ribonucleotide reductase M2 B (TP53 inducible)). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
p53R2
Description (Vector)
Plays a pivotal role in cell survival by repairing damaged DNA in a p53/TP53-dependent manner. Supplies deoxyribonucleotides for DNA repair in cells arrested at G1 or G2. Contains an iron-tyrosyl free radical center required for catalysis. Forms an active ribonucleotide reductase (RNR) complex with RRM1 which is expressed both in resting and proliferating cells in response to DNA damage.
Gene ID
382985
Gene Name (Vector)
ribonucleotide reductase M2 B (TP53 inducible)
Gene Symbol
Rrm2b
ORF Size (aa)
1056
ORF Size (bp)
1056 bp
RefSeq ID
NM_199476
RefSeq Synonyms
NM_199476, BC058103,
Species
mouse
UniGene ID
Mm.24738
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.