mouse RNF19A shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Rnf19a.
shAAV-270721
AAV-m-RNF19A-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Rnf19a (ring finger protein 19A). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AA032313; Dorfin; Rnf19; Ubce7ip2; UIP117; XYbp
Description (Vector)
E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates, such as SNCAIP or CASR. Specifically ubiquitinates pathogenic SOD1 variants, which leads to their proteasomal degradation and to neuronal protection.
Gene ID
30945
Gene Name (Vector)
ring finger protein 19A
Gene Symbol
Rnf19a
ORF Size (aa)
2523
ORF Size (bp)
2523 bp
RefSeq ID
NM_013923
RefSeq Synonyms
NM_013923, BC040769,
Species
mouse
UniGene ID
Mm.5181
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.