mouse RBM38 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Rbm38.
shAAV-270250
AAV-m-RBM38-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Rbm38 (RNA binding motif protein 38). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Rnpc1; Seb4; Seb4l
Description (Vector)
RNA-binding protein that specifically bind the 3'-UTR of CDKN1A transcripts, leading to maintain the stability of CDKN1A transcripts, thereby acting as a mediator of the p53/TP53 family to regulate CDKN1A. CDKN1A is a cyclin-dependent kinase inhibitor transcriptionally regulated by the p53/TP53 family to induce cell cycle arrest. Isoform 1, but not isoform 2, has the ability to induce cell cycle arrest in G1 and maintain the stability of CDKN1A transcripts induced by p53/TP53. Also acts as a mRNA splicing factor. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Plays a role in myogenic differentiation.
Gene ID
56190
Gene Name (Vector)
RNA binding motif protein 38
Gene Symbol
Rbm38
ORF Size (aa)
714
RefSeq ID
NM_019547
RefSeq Synonyms
NM_019547, BC085307,
Species
mouse
UniGene ID
Mm.3865
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.