mouse RASGRP2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Rasgrp2.
shAAV-270175
AAV-m-RASGRP2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Rasgrp2 (RAS, guanyl releasing protein 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Caldaggef1; CDC25L
Description (Vector)
Functions as a calcium- and DAG-regulated nucleotide exchange factor specifically activating Rap through the exchange of bound GDP for GTP. May also activates other GTPases such as RRAS, RRAS2, NRAS, KRAS but not HRAS. Functions in aggregation of platelets and adhesion of T-lymphocytes and neutrophils probably through inside-out integrin activation. May function in the muscarinic acetylcholine receptor M1/CHRM1 signaling pathway.
Gene ID
19395
Gene Name (Vector)
RAS, guanyl releasing protein 2
Gene Symbol
Rasgrp2
ORF Size (aa)
1824
ORF Size (bp)
1824 bp
RefSeq ID
NM_011242
RefSeq Synonyms
NM_011242, BC148631,
Species
mouse
UniGene ID
Mm.77017
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.