mouse RAD18 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Rad18.
shAAV-270053
AAV-m-RAD18-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Rad18 (RAD18 E3 ubiquitin protein ligase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
2810024C04Rik; Rad18sc
Description (Vector)
E3 ubiquitin-protein ligase involved in postreplication repair of UV-damaged DNA. Postreplication repair functions in gap-filling of a daughter strand on replication of damaged DNA. Associates to the E2 ubiquitin conjugating enzyme UBE2B to form the UBE2B-RAD18 ubiquitin ligase complex involved in mono-ubiquitination of DNA-associated PCNA on 'Lys-164'. Has ssDNA binding activity.
Gene ID
58186
Gene Name (Vector)
RAD18 E3 ubiquitin protein ligase
Gene Symbol
Rad18
ORF Size (aa)
930
ORF Size (bp)
930 bp
RefSeq ID
NM_021385
RefSeq Synonyms
NM_021385, NM_001167730, BC011120,
Species
mouse
UniGene ID
Mm.103812
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.