mouse RAB3IP shRNA silencing AAV

Name 
AAV-m-RAB3IP-shRNA
Cat No 
shAAV-270004
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Rab3ip.

shAAV-270004
AAV-m-RAB3IP-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Rab3ip (RAB3A interacting protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
B230311A06; Gtpat12; Rabin3
Description (Vector)
Guanine nucleotide exchange factor for RAB8A. Mediates the release of GDP from RAB8A but not from RAB3A or RAB5. Modulates actin organization and promotes polarized transport of RAB8A-specific vesicles to the cell surface. Together with RAB11A, RAB8A, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis.
Gene ID
216363
Gene Name (Vector)
RAB3A interacting protein
Gene Symbol
Rab3ip
ORF Size (aa)
1287
ORF Size (bp)
1287 bp
RefSeq ID
NM_001003950
RefSeq Synonyms
NM_001003950, BC080289,
Species
mouse
UniGene ID
Mm.336394

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.