mouse PZP shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Pzp.
shAAV-269911
AAV-m-PZP-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Pzp (pregnancy zone protein). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
A1m; A2m; AI893533; MAM
Description (Vector)
Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase.
Gene ID
11287
Gene Name (Vector)
pregnancy zone protein
Gene Symbol
Pzp
ORF Size (aa)
4488
ORF Size (bp)
4488 bp
RefSeq ID
NM_007376
RefSeq Synonyms
NM_007376, BC057983,
Species
mouse
UniGene ID
Mm.260144
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.