mouse PTPRR shRNA silencing AAV

Name
AAV-m-PTPRR-shRNA

Cat No
shAAV-269829

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Mouse Ptprr.

shAAV-269829

AAV-m-PTPRR-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Ptprr (protein tyrosine phosphatase, receptor type, R). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

Gmcp1; mPTP213; PTP-SL; PTPBR7; RPTPRR

Description (Vector)

Sequesters mitogen-activated protein kinases (MAPKs) such as MAPK1, MAPK3 and MAPK14 in the cytoplasm in an inactive form. The MAPKs bind to a dephosphorylated kinase interacting motif, phosphorylation of which by the protein kinase A complex releases the MAPKs for activation and translocation into the nucleus (By similarity).

Gene ID

19279

Gene Name (Vector)

protein tyrosine phosphatase, receptor type, R

Gene Symbol

Ptprr

ORF Size (aa)

1971

ORF Size (bp)

1971 bp

RefSeq ID

NM_011217

RefSeq Synonyms

NM_011217, NM_001161840, NM_001161839, NM_001161838, NM_001161837, BC120547, BC119230,

Species

mouse

UniGene ID

Mm.336316

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.