mouse PTPN11 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Ptpn11.
shAAV-269792
AAV-m-PTPN11-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Ptpn11 (protein tyrosine phosphatase, non-receptor type 11). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
2700084A17Rik; AW536184; PTP1D; PTP2C; SAP-2; SH-PTP2; SH-PTP3; SHP-2; Shp2; Syp
Description (Vector)
Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Dephosphorylates ROCK2 at Tyr-722 resulting in stimulatation of its RhoA binding activity.
Gene ID
19247
Gene Name (Vector)
protein tyrosine phosphatase, non-receptor type 11
Gene Symbol
Ptpn11
ORF Size (aa)
1782
ORF Size (bp)
1782 bp
RefSeq ID
NM_011202
RefSeq Synonyms
NM_011202, NM_001109992, BC059278, BC057398,
Species
mouse
UniGene ID
Mm.474046
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.