mouse PTN shRNA silencing AAV

Name 
AAV-m-PTN-shRNA
Cat No 
shAAV-269773
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Ptn.

shAAV-269773
AAV-m-PTN-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Ptn (pleiotrophin). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
HARP; HB-GAM; HBBN; HBGF-8; HBNF; OSF; Osf-1; Osf1
Description (Vector)
Secreted growth factor that induces neurite outgrowth and which is mitogenic for fibroblasts, epithelial, and endothelial cells. Binds anaplastic lymphoma kinase (ALK) which induces MAPK pathway activation, an important step in the anti-apoptotic signaling of PTN and regulation of cell proliferation.
Gene ID
19242
Gene Name (Vector)
pleiotrophin
Gene Symbol
Ptn
ORF Size (aa)
507
RefSeq ID
NM_008973
RefSeq Synonyms
NM_008973, BC061695, BC002064,
Species
mouse
UniGene ID
Mm.279690

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.