mouse FSTL3 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Fstl3.
shAAV-269574
AAV-m-FSTL3-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Fstl3 (follistatin-like 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
E030038F23Rik; Flrg
Description (Vector)
Isoform 1 or the secreted form is a binding and antagonizing protein for members of the TGF-beta family, such us activin, BMP2 and MSTN. Inhibits activin A-, activin B-, BMP2- and MSDT-induced cellular signaling; more effective on activin A than on activin B. Involved in bone formation; inhibits osteoclast differentiationc. Involved in hematopoiesis; involved in differentiation of hemopoietic progenitor cells, increases hematopoietic cell adhesion to fibronectin and seems to contribute to the adhesion of hematopoietic precursor cells to the bone marrow stroma. Isoform 2 or the nuclear form is probably involved in transcriptional regulation via interaction with MLLT10.
Gene ID
83554
Gene Name (Vector)
follistatin-like 3
Gene Symbol
Fstl3
ORF Size (aa)
771
ORF Size (bp)
771 bp
RefSeq ID
NM_031380
RefSeq Synonyms
NM_031380, BC061052,
Species
mouse
UniGene ID
Mm.251710
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.