mouse PROM1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Prom1.
shAAV-269471
AAV-m-PROM1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Prom1 (prominin 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
4932416E19Rik; AC133; CD133; Prom; Prom-1; Proml1
Description (Vector)
Binds cholesterol in cholesterol-containing plasma membrane microdomains. Proposed to play a role in apical plasma membrane organization of epithelial cells. During early retinal development acts as a key regulator of disk morphogenesis. Involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner.
Gene ID
19126
Gene Name (Vector)
prominin 1
Gene Symbol
Prom1
ORF Size (aa)
2529
ORF Size (bp)
2529 bp
RefSeq ID
NM_008935
RefSeq Synonyms
NM_008935, NM_001163585, NM_001163584, NM_001163583, NM_001163582, NM_001163581, NM_001163578, NM_001163577, BC028286,
Species
mouse
UniGene ID
Mm.6250
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.