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mouse PRKACB shRNA silencing AAV

Name 
AAV-m-PRKACB-shRNA
Cat No 
shAAV-269364
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Prkacb.

shAAV-269364
AAV-m-PRKACB-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Prkacb (protein kinase, cAMP dependent, catalytic, beta). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CbPKA; Pkacb
Description (Vector)
Mediates cAMP-dependent signaling triggered by receptor binding to GPCRs. PKA activation regulates diverse cellular processes such as cell proliferation, the cell cycle, differentiation and regulation of microtubule dynamics, chromatin condensation and decondensation, nuclear envelope disassembly and reassembly, as well as regulation of intracellular transport mechanisms and ion flux. Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis.
Gene ID
18749
Gene Name (Vector)
protein kinase, cAMP dependent, catalytic, beta
Gene Symbol
Prkacb
ORF Size (aa)
1056
ORF Size (bp)
1056 bp
RefSeq ID
NM_011100
RefSeq Synonyms
NM_011100, NM_001164200, NM_001164199, NM_001164198, BC054533,
Species
mouse
UniGene ID
Mm.16766

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.