mouse PREX1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Prex1.
shAAV-269340
AAV-m-PREX1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Prex1 (phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
G630042G04; P-REX1; Setd6
Description (Vector)
Functions as a RAC guanine nucleotide exchange factor (GEF), which activates the Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol 3,4,5-trisphosphate and the beta gamma subunits of heterotrimeric G protein. May function downstream of heterotrimeric G proteins in neutrophils.
Gene ID
277360
Gene Name (Vector)
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
Gene Symbol
Prex1
ORF Size (aa)
4953
ORF Size (bp)
4953 bp
RefSeq ID
NM_177782
RefSeq Synonyms
NM_177782, BC157940, BC151074,
Species
mouse
UniGene ID
Mm.395887
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.