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mouse PPP2R2D shRNA silencing AAV

Name 
AAV-m-PPP2R2D-shRNA
Cat No 
shAAV-269233
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Ppp2r2d.

shAAV-269233
AAV-m-PPP2R2D-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Ppp2r2d (protein phosphatase 2, regulatory subunit B, delta). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
1300017E19Rik; D7Ertd753e; MDS026
Description (Vector)
B regulatory subunit of protein phosphatase 2A (PP2A) that plays a key role in cell cycle by controlling mitosis entry and exit. The activity of PP2A complexes containing PPP2R2D (PR55-delta) fluctuate during the cell cycle: the activity is high in interphase and low in mitosis. During mitosis, activity of PP2A is inhibited via interaction with phosphorylated ENSA and ARPP19 inhibitors. Within the PP2A complexes, the B regulatory subunits modulate substrate selectivity and catalytic activity, and also may direct the localization of the catalytic enzyme to a particular subcellular compartment (By similarity).
Gene ID
52432
Gene Name (Vector)
protein phosphatase 2, regulatory subunit B, delta
Gene Symbol
Ppp2r2d
ORF Size (aa)
1362
ORF Size (bp)
1362 bp
RefSeq ID
NM_026391
RefSeq Synonyms
NM_026391, NM_001347618, BC066022,
Species
mouse
UniGene ID
Mm.258739

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.