mouse PPP1R3B shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Ppp1r3b.
shAAV-269215
AAV-m-PPP1R3B-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Ppp1r3b (protein phosphatase 1, regulatory (inhibitor) subunit 3B). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
6430576E21; AW821953; GL; PTG
Description (Vector)
Acts as a glycogen-targeting subunit for phosphatase PP1. Facilitates interaction of the PP1 with enzymes of the glycogen metabolism and regulates its activity. Suppresses the rate at which PP1 dephosphorylates (inactivates) glycogen phosphorylase and enhances the rate at which it activates glycogen synthase and therefore limits glycogen breakdown. Its activity is inhibited by PYGL, resulting in inhibition of the glycogen synthase and glycogen phosphorylase phosphatase activities of PP1. Dramatically increases basal and insulin-stimulated glycogen synthesis upon overexpression in hepatocytes (By similarity).
Gene ID
244416
Gene Name (Vector)
protein phosphatase 1, regulatory (inhibitor) subunit 3B
Gene Symbol
Ppp1r3b
ORF Size (aa)
855
ORF Size (bp)
855 bp
RefSeq ID
NM_177741
RefSeq Synonyms
NM_177741, BC079666,
Species
mouse
UniGene ID
Mm.247126
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.