mouse PPP1R16B shRNA silencing AAV

Name 
AAV-m-PPP1R16B-shRNA
Cat No 
shAAV-269204
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Ppp1r16b.

shAAV-269204
AAV-m-PPP1R16B-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Ppp1r16b (protein phosphatase 1, regulatory (inhibitor) subunit 16B). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ANKRD4; C130078N17Rik; TIMAP; Wdt4
Description (Vector)
Regulator of protein phosphatase 1 (PP1) that acts as a positive regulator of pulmonary endothelial cell (EC) barrier function. Involved in PKA-mediated moesin dephosphorylation which is important in EC barrier protection against thrombin stimulation. Promotes the interaction of PPP1CA with RPSA/LAMR1 and in turn facilitates the dephosphorylation of RPSA/LAMR1. Involved in the regulation of endothelial cell filopodia extension. May be a downstream target for TGF-beta1 signaling cascade in endothelial cells.
Gene ID
228852
Gene Name (Vector)
protein phosphatase 1, regulatory (inhibitor) subunit 16B
Gene Symbol
Ppp1r16b
ORF Size (aa)
1707
ORF Size (bp)
1707 bp
RefSeq ID
NM_153089
RefSeq Synonyms
NM_153089, NM_001159662, BC057542, BC054764,
Species
mouse
UniGene ID
Mm.392383

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.