human GUCY2F Over-expression AAV

Name 
AAV-h-GUCY2F
Cat No 
AAV-210693
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human GUCY2F.

AAV-210693
AAV-h-GUCY2F

Ready-to-use AAV expressing Human GUCY2F (guanylate cyclase 2F, retinal). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CYGF; GC-F; GUC2DL; GUC2F; RETGC-2; ROS-GC2
Description (Vector)
GUCY2F is a guanylyl cyclase found predominantly in photoreceptors in the retina. The encoded protein is thought to be involved in resynthesis of cGMP after light activation of the visual signal transduction cascade, allowing a return to the dark state. This protein is a single-pass type I membrane protein. Defects in this gene may be a cause of X-linked retinitis pigmentosa.
Gene ID
2986
Gene Name (Vector)
guanylate cyclase 2F, retinal
Gene Symbol
GUCY2F
HGNC ID
HGNC:4691
ORF Size (aa)
3327
ORF Size (bp)
3327 bp
RefSeq ID
NM_001522
RefSeq Synonyms
NM_001522, BC156674,
Species
human
UniGene ID
Hs.123074

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.