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mouse PPARGC1B shRNA silencing AAV

Name 
AAV-m-PPARGC1B-shRNA
Cat No 
shAAV-269124
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Ppargc1b.

shAAV-269124
AAV-m-PPARGC1B-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Ppargc1b (peroxisome proliferative activated receptor, gamma, coactivator 1 beta). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
4631412G21Rik; Perc
Description (Vector)
Plays a role of stimulator of transcription factors and nuclear receptors activities. Activates transcritional activity of estrogen receptor alpha, nuclear respiratory factor 1 (NRF1) and glucocorticoid receptor in the presence of glucocorticoids. May play a role in constitutive non-adrenergic-mediated mitochondrial biogenesis as suggested by increased basal oxygen consumption and mitochondrial number when overexpressed. May be involved in fat oxidation and non-oxidative glucose metabolism and in the regulation of energy expenditure.
Gene ID
170826
Gene Name (Vector)
peroxisome proliferative activated receptor, gamma, coactivator 1 beta
Gene Symbol
Ppargc1b
ORF Size (aa)
3045
ORF Size (bp)
3045 bp
RefSeq ID
NM_133249
RefSeq Synonyms
NM_133249, BC150699,
Species
mouse
UniGene ID
Mm.415302

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.