mouse PPAPDC2 shRNA silencing AAV

Name 
AAV-m-PPAPDC2-shRNA
Cat No 
shAAV-269118
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Plpp6.

shAAV-269118
AAV-m-PPAPDC2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Plpp6 (phospholipid phosphatase 6). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
4932443D16Rik; Ppapdc2
Description (Vector)
Phosphatase that dephosphorylates presqualene diphosphate (PSDP) into presqualene monophosphate (PSMP), suggesting that it may be indirectly involved in innate immunity. PSDP is a bioactive lipid that rapidly remodels to presqualene monophosphate PSMP upon cell activation. Displays diphosphate phosphatase activity with a substrate preference for PSDP > FDP > phosphatidic acid.
Gene ID
74411
Gene Name (Vector)
phospholipid phosphatase 6
Gene Symbol
Plpp6
ORF Size (aa)
879
RefSeq ID
NM_028922
RefSeq Synonyms
NM_028922, BC052412,
Species
mouse
UniGene ID
Mm.441887

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.