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mouse PLCG1 shRNA silencing AAV

Name 
AAV-m-PLCG1-shRNA
Cat No 
shAAV-268824
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Plcg1.

shAAV-268824
AAV-m-PLCG1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Plcg1 (phospholipase C, gamma 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AI894140; Cded; Plc-1; Plc-gamma1; Plcg-1
Description (Vector)
Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. Becomes activated in response to ligand-mediated activation of receptor-type tyrosine kinases, such as PDGFRA, PDGFRB, FGFR1, FGFR2, FGFR3 and FGFR4. Plays a role in actin reorganization and cell migration.
Gene ID
18803
Gene Name (Vector)
phospholipase C, gamma 1
Gene Symbol
Plcg1
ORF Size (aa)
3909
ORF Size (bp)
3909 bp
RefSeq ID
NM_021280
RefSeq Synonyms
NM_021280, BC065091,
Species
mouse
UniGene ID
Mm.44463

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.