mouse PKMYT1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Pkmyt1.
shAAV-268738
AAV-m-PKMYT1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Pkmyt1 (protein kinase, membrane associated tyrosine/threonine 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
6230424P17; AW209059; Myt1
Description (Vector)
Acts as a negative regulator of entry into mitosis (G2 to M transition) by phosphorylation of the CDK1 kinase specifically when CDK1 is complexed to cyclins. Mediates phosphorylation of CDK1 predominantly on 'Thr-14'. Also involved in Golgi fragmentation. May be involved in phosphorylation of CDK1 on 'Tyr-15' to a lesser degree, however tyrosine kinase activity is unclear and may be indirect. May be a downstream target of Notch signaling pathway during eye development.
Gene ID
268930
Gene Name (Vector)
protein kinase, membrane associated tyrosine/threonine 1
Gene Symbol
Pkmyt1
ORF Size (aa)
1473
ORF Size (bp)
1473 bp
RefSeq ID
NM_023058
RefSeq Synonyms
NM_023058, BC025061,
Species
mouse
UniGene ID
Mm.182193
Recently Viewed Products
Ad-CMV-Luc
Cat No: 1000
Ad-CMV-Akt1 (Myr)
Cat No: 1020
Ad-CMV-Akt1 (dn)
Cat No: 1021
Ad-CMV-Akt1 (wt)
Cat No: 1022
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.