mouse PELI2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Peli2.
shAAV-268388
AAV-m-PELI2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Peli2 (pellino 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AW047589; BB129927
Description (Vector)
E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Involved in the TLR and IL-1 signaling pathways via interaction with the complex containing IRAK kinases and TRAF6. Mediates 'Lys-63'-linked polyubiquitination of IRAK1. Can activate the MAP (mitogen activated protein) kinase pathway leading to activation of ELK1. Not required for NF-kappa-B activation.
Gene ID
93834
Gene Name (Vector)
pellino 2
Gene Symbol
Peli2
ORF Size (aa)
960
ORF Size (bp)
960 bp
RefSeq ID
NM_033602
RefSeq Synonyms
NM_033602, BC027062,
Species
mouse
UniGene ID
Mm.296457
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.