mouse PAX4 shRNA silencing AAV

Name
AAV-m-PAX4-shRNA

Cat No
shAAV-268110

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Mouse Pax4.

shAAV-268110

AAV-m-PAX4-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Pax4 (paired box 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

Pax-4

Description (Vector)

Plays an important role in the differentiation and development of pancreatic islet beta cells. Transcriptional repressor that binds to a common element in the glucagon, insulin and somatostatin promoters. Competes with PAX6 for this same promoter binding site. Isoform 2 appears to be a dominant negative form antagonizing PAX4 transcriptional activity.

Gene ID

18506

Gene Name (Vector)

paired box 4

Gene Symbol

Pax4

ORF Size (aa)

1008

ORF Size (bp)

1008 bp

RefSeq ID

NM_011038

RefSeq Synonyms

NM_011038, NM_001159926, NM_001159925, BC145169, BC145168, BC131908, BC131906,

Species

mouse

UniGene ID

Mm.8026

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.