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mouse PARP3 shRNA silencing AAV

Name 
AAV-m-PARP3-shRNA
Cat No 
shAAV-268081
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Parp3.

shAAV-268081
AAV-m-PARP3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Parp3 (poly (ADP-ribose) polymerase family, member 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
A930002C11Rik; Adprt3; Adprtl3; AW990611; pADPRT-3; PARP-3
Description (Vector)
Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. May link the DNA damage surveillance network to the mitotic fidelity checkpoint. Negatively influences the G1/S cell cycle progression without interfering with centrosome duplication. Binds DNA. May be involved in the regulation of PRC2 and PRC3 complex-dependent gene silencing.
Gene ID
235587
Gene Name (Vector)
poly (ADP-ribose) polymerase family, member 3
Gene Symbol
Parp3
ORF Size (aa)
1587
ORF Size (bp)
1587 bp
RefSeq ID
NM_145619
RefSeq Synonyms
NM_145619, NM_001311150, BC058754, BC014870,
Species
mouse
UniGene ID
Mm.273659

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.