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mouse PAIP2 shRNA silencing AAV

Name 
AAV-m-PAIP2-shRNA
Cat No 
shAAV-268012
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Paip2.

shAAV-268012
AAV-m-PAIP2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Paip2 (polyadenylate-binding protein-interacting protein 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
2310050K10Rik; AU045972
Description (Vector)
Acts as a repressor in the regulation of translation initiation of poly(A)-containing mRNAs. Its inhibitory activity on translation is mediated via its action on PABPC1. Displaces the interaction of PABPC1 with poly(A) RNA and competes with PAIP1 for binding to PABPC1. Its association with PABPC1 results in disruption of the cytoplasmic poly(A) RNP structure organization.
Gene ID
67869
Gene Name (Vector)
polyadenylate-binding protein-interacting protein 2
Gene Symbol
Paip2
ORF Size (aa)
375
ORF Size (bp)
375 bp
RefSeq ID
NM_026420
RefSeq Synonyms
NM_026420, BC010190,
Species
mouse
UniGene ID
Mm.126534

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.