mouse PACS1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Pacs1.
shAAV-267986
AAV-m-PACS1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Pacs1 (phosphofurin acidic cluster sorting protein 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AI325977
Description (Vector)
Coat protein that is involved in the localization of trans-Golgi network (TGN) membrane proteins that contain acidic cluster sorting motifs. Controls the endosome-to-Golgi trafficking of furin and mannose-6-phosphate receptor by connecting the acidic-cluster-containing cytoplasmic domain of these molecules with the adapter-protein complex-1 (AP-1) of endosomal clathrin-coated membrane pits. Involved in HIV-1 nef-mediated removal of MHC-I from the cell surface to the TGN.
Gene ID
107975
Gene Name (Vector)
phosphofurin acidic cluster sorting protein 1
Gene Symbol
Pacs1
ORF Size (aa)
2886
ORF Size (bp)
2886 bp
RefSeq ID
NM_153129
RefSeq Synonyms
NM_153129, BC062886,
Species
mouse
UniGene ID
Mm.234923
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.